Which statement about neutrophil granules is true?

• A. Neutral or white
• B. Blue
• C. Red
• D. Yellow

Answer: (A)

The main idea is how neutrophil granules stain in common histology preparations. Neutrophil granules are described as neutral-staining, meaning they don’t take up basic or acidic dyes strongly and often appear colorless or pale on routine stains. This contrasts with other granulocytes: eosinophils have reddish-orange granules and basophils have blue-to-purple granules. While neutrophils do contain some azurophilic granules that can stain dark with certain methods, the typical appearance on standard Wright-Giemsa stains is neutral or white granules. So, describing their granules as neutral or white best fits the usual staining pattern.